(See "Hemiplegic migraine", section on 'Medications generally avoided' and "Migraine with brainstem aura", section on 'Medications to avoid' . Apr 1, 2016 · 1U Botox/Xeomin = 2. 415. Apr 5, 2024 · Dysport works by temporarily blocking the communication between nerves and muscles. Hence, the disease imposes a heavy burden on society . Nov 2, 2022 · Getting Botox and similar medications (Dysport, Jeuveau, and Xeomin) is one of the most popular cosmetic procedures that you can have without surgery. The LAMP, as seen in Supplemental Figure 1, (Dysport®) for migraine without aura. Table 2: DYSPORT Dosing by Muscle for Adult Upper Limb Spasticity . Dysport® is thought to have a more diffuse distribution of effect (greater spread than Botox®). Therapeutically, it helps address muscle stiffness and relieve migraines. 1 Botulinum toxin type A is recommended as an option for the prophylaxis of headaches in adults with chronic migraine (defined as headaches on at least 15 days per month of which at least 8 days are with migraine): Botox and Dysport have helped many people with their migraines, could it help you? Learn how this works, and what your options are, here. Migraine, as a disease with a genetic background, has a controversial pathogenesis due to the diversity of factors affecting it. Chronic migraine is when you experience headaches for 15 days per month or more, and where 8 days of which are migraine headaches. Before getting Botox, you’ll be asked to avoid alcohol Clear dosing for adult upper limb spasticity . We found nothing new that affects the recommendations in this guidance. CPT Code . 2011; 51 (1): 52-63. A migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head, and is often accompanied by feeling or being sick and a sensitivity to Nov 16, 2010 · A 12-week, double-blind, randomized trial of Dysport (120 or 240 units) vs placebo was conducted in 6 centers in Thailand to evaluate the efficacy, safety, and optimum dose of botulinum toxin type-A (Dysport) for migraine prophylaxis. What is Dysport . For continuing Botulism toxin therapy the patients must demonstrate a significant decrease in the number and frequency of headaches and an improvement in function Migraine Headache Botox . Dysport, a neurotoxin similar to Botox, has gained attention as a potential solution for migraine relief. Although not all of these side effects may occur, if they do occur they may need medical attention. This therapy works best for people who experience headaches at least 15 days out of every month. 3 Spasticity in Adults Yes, Dysport has been approved by the FDA to treat chronic migraines and TMJ. 1 VACUUM When reconstituting Dysport, insert the needle into the vial and allow the diluent to be The effects of DYSPORT may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. safely and effectively. ) We would like to show you a description here but the site won’t allow us. Apr 6, 2022 · How does Botox for migraines work? Botox injections are U. Jun 27, 2012 · 1 Guidance. A migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head, and is often accompanied by feeling or being sick and a sensitivity to Dysport® (abobotulinumtoxinA) - Official Patient Website Clinical Review Suhail Kasim, M. BOTOX has been used at the recommended dose to treat chronic migraine, severe underarm sweating, Dysport® , or Xeomin® • have a skin infection at the planned injection site Jul 3, 2024 · The purpose of this study is to understand the safety and effectiveness of the study drug, Dysport® when compared with placebo in preventing episodic migraine. With uncertain conversion factors ranging from 1:2 to 1:5 between the potency labelling of ONA/INCO and ABO, we found it unsafe to include ABO. Objectives To assess the effects of botulinum toxin for prevention of migraine in adults. Google Scholar. Don’t drink alcohol. A movement disorder partner highly committed to empowering you through appropriate support along with lasting spasticity and cervical dystonia relief. Dysport injections have been used safely and effectively for over 15 years to treat many ophthalmologic and neurologic disorders. 1. g. , Dysport®), work by inhibiting the release of chemical messengers like calcitonin gene-related peptide (CGRP) that cause pain. Eligibility criteria We included randomised controlled trials (RCTs) of botulinum toxin compared with placebo, active treatment or clinically relevant different dose for adults with chronic or episodic Dec 27, 2018 · Live your most beautiful life!; https://www. It is well known for its ability to reduce and smooth facial wrinkles, but it can also be an effective treatment for the prevention of chronic migraine. It is thought that BOTOX® blocks the pain signals that migraines cause. The most common side effects of Dysport include: Temporary soreness or mild bruising around the injection site. the risks of you taking Dysport against the benefits they expect it will have for you. Injection site infection. Jan 18, 2023 · Though Dysport, Botox, or other botulinum toxin-based therapies are generally well tolerated and minimally invasive, these therapies may not be a good fit for certain people. 1 Dysport helps them look consistently natural—not frozen—because it allows the untreated facial muscles to work normally, which in turn helps patients freely show facial expressions in untreated areas. 64612 Chemodenervation of muscle(s); muscle(s) innervated by facial nerve (eg, for blepharospasm, hemifacial spasm) Dysport potency units are not interchangeable with other preparations of botulinum toxin products 1; When treating adults with spasticity, no more than 1 mL should generally be administered at any single injection site 1 Jun 13, 2022 · Chronic migraine is far more debilitating and is associated with higher rates of anxiety and depression . See full prescribing information for DYSPORT. Let patients know that BOTOX ® is a locally administered procedure that takes about 10 minutes once every 3 months and the injections may feel like tiny pinches. 1 Units of biological activity of Dysport cannot be compared to or converted into units of any other botulinum toxin products Nov 1, 2010 · To evaluate the efficacy, safety, and optimum dose of a highly purified Clostridium botulinum type A toxin-hemagglutinin complex (Dysport) for migraine prophylaxis. How we develop NICE technology appraisal guidance. sonataskinandbody. Jul 5, 2024 · Migraine subtypes – Triptans are avoided in patients with hemiplegic migraine or migraine with brainstem aura due to the theoretical risk of cerebral vasoconstriction. Criteria B and C for migraine with aura 3. Jul 24, 2015 · Although Botox (onabotulinumtoxinA), Dysport (abobotulinumtoxinA), Xeomin (incobotulinumtoxinA) or Myobloc (rimabotulinumtoxinB) have been approved for use by the U. Onabotulinumtoxin A, targeting the machinery for exocytosis of neurotransmitters and neuropeptides, has been approved for use in chronic migraine Apr 21, 2018 · Answer: Protocol after Botox/Xeomin/Dysport for Migraines--Results Resolve in 3-4 months I recommend following up with your injector about after care following your Botox treatment. Tension-type Headaches Moderate Evidence No new studies were identified that would have changed the conclusion of the 2008 guideline. Initial Authorization Criteria ALL of the following are met: • Age 18 years or older • Diagnosis of chronic migraine headache as defined by 15 days or more per month with headache lasting four hours a day or longer • Documentation of ONE of the following: o Failure following a minimum 8 week trial of TWO migraine Jun 18, 2019 · According to the third criterion, AR is classified as either mild or moderate/severe (original ARIA classification, oARIA), depending on the impact of the disease on the following quality-of-life measures [] (Figure 1): a) daily activities and sport, b) school/work attendance, c) sleep, and d) need of therapy, as reported by the patient. , M. Approximately 44. The recommended total dose of Botox (onabotulinumtoxinA) for chronic migraine prevention is 155 Units administered into a muscle (intramuscularly). Temporary eyelid droop (ptosis). May 29, 2024 · SMD form protocol master data–5- INT / Version 1 In the second Treatment Phase, all participants will get Dysport® (Dose A or Dose B). Max Units (per dose and over time) [Medical Benefit]: Indication Billable Units Per # days Cervical Dystonia 200 84 Upper Limb Spasticity 200 84 Chronic Migraine Prophylaxis 100 84 Sialorrhea 100 84 May 4, 2023 · • Patient is utilizing prophylactic intervention modalities (i. Dec 30, 2022 · Chronic migraine; Spastic neck or limb muscles; Some cases of crossed eyes and eye twitching; In contrast, Dysport is currently only approved for relieving severe glabellar furrowing and spasticity of the neck and limbs. org. Out of pocket I think it would be ~$900 (I asked out of curiosity). 2) and Description (11)]. They approved me for Dysport in 24 hrs which was the fastest that they had seen. Before you receive a Dysport injection tell your doctor: Natural looking Dysport provides temporary improvement in the appearance of moderate to severe frown lines that are caused by the activity of the procerus and corrugator muscles in patients. Many patients have expressed that they receive differing information on what to do prior to and following their Botox treatments. 1 mL (5 Units) injections divided across 7 specific head and neck muscle areas, for a total of 31 individual injections per session. Headache. Patients with migraine report severe throbbing pain, neck pain, nausea, vomiting, sensitivity to light and sound. Feb 22, 2024 · It is a prescription drug used to prevent headaches in people aged 18 years and above with chronic migraines (severe, throbbing headaches occasionally accompanied by nausea and sensitivity to sound or light). 1 * * In clinical trials, the primary endpoint for cervical dystonia was based on the total Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) change at Week 4. Enrollment 138 patients Prophylactic botulinum type A toxin complex (Dysport®) for migraine without aura: Authors: Siwaporn Chankrachang Arkhom Arayawichanont Niphon Poungvarin Samart Nidhinandana Pairoj Boonkongchuen Somchai Towanabut Pasiri Sithinamsuwan Subsai Kongsaengdao: Authors: Siwaporn Chankrachang Arkhom Arayawichanont Niphon Poungvarin Samart Nidhinandana the risks of you taking Dysport against the benefits they expect it will have for you. Chronic migraine is very disabling, being characterized by at least 15 headache days per month of which at least 8 days present the features of migraine. Botox is effective for migraine lasting 15 or more days each month, with headaches lasting four hours a day or longer. Overcome hesitation with education about BOTOX ®. Unlike many other injections, migraine treatment with Botox requires several injections at various locations around the head and face. BOTOX ® (onabotulinumtoxinA) is a prescription medicine that is injected into muscles and used to prevent headaches in adults with chronic migraine who have 15 or more days each month with headache lasting 4 or more hours each day in people 18 years and older. It should be fine to apply cosmetics and wash your hair/face after your treatment. These symptoms have ® ® HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use DYSPORT. Botox, or onabotulinum toxin A, is a drug made from the bacteria Colistridium botulinum. S. The higher burden of chronic migraine further necessitates the need for better treatment in this subgroup of patients. Allergy to cow milk protein. Exercise caution when administering to patients with surgical alterations to facial anatomy, excessive weakness or atrophy in the target muscle(s), marked facial asymmetry, inflammation at the injection site(s), ptosis, excessive dermatochalasis, deep dermal scarring, thick sebaceous skin or Jul 11, 2023 · Oh no, I am so sorry. Approach to Pediatric Intractable METHODS: A 12-week, double-blind, randomized trial of Dysport (120 or 240 units) vs placebo was conducted in 6 centers in Thailand to evaluate the efficacy, safety, and optimum dose of botulinum toxin type-A (Dysport) for migraine prophylaxis. 5U Dysport. Along with its needed effects, abobotulinumtoxinA (the active ingredient contained in Dysport) may cause some unwanted effects. • Reconstituted DYSPORT is intended for intramuscular injection only. The insurance is billed $1400 for each round of treatment (every 2 months). We would like to show you a description here but the site won’t allow us. Headaches emanating from temporal regions may be treated with similar doses of Dysport (split between the two We would like to show you a description here but the site won’t allow us. Cosmetically, it can prevent muscles from causing wrinkles on the skin. com, 303-469-0064, the office of Lawrence Janowski, MD, est. I don’t have this issue, but my dermatologist (board certified in laser, cosmetic, and MOHS surgery and also teaches other physicians re these neuromodulator treatments) injects in multiple spots around the face. migraine day; MPFID, Migraine Physical Function Impact Diary; MSQ, Migraine-Specific Quality of Life; mTOQ, Migraine Treatment Optimization Questionnaire; NSAID, nonsteroidal anti-inflammatory drug; PGIC, Patient Global Impression of Change; PPMQ-R, Patient Perception of Migraine Questionnaire-Revised; SC, subcutaneous; WPAI, Work Productivity and Nov 16, 2010 · A 12-week, double-blind, randomized trial of Dysport (120 or 240 units) vs placebo was conducted in 6 centers in Thailand to evaluate the efficacy, safety, and optimum dose of botulinum toxin type-A (Dysport) for migraine prophylaxis. The potency units of DYSPORT are not interchangeable with other preparations of botulinum toxin products and, therefore, units of biological activity of DYSPORT cannot be compared to or converted into units of any other botulinum toxin products assessed with any other specific assay method [see Warnings and Precautions (5. When injected into specific areas of the head and neck, Dysport can prevent the onset of migraines in individuals who suffer from chronic migraines. ); AND • Patient has a diagnosis of chronic migraines defined as 15 or more headache (tension-type-like and/or migraine-like) days per month for > 3 months; AND Contraindications. Criteria C and D for migraine without aura 2. 4 Feb 15, 2018 · Migraine is a primary headache disorder characterized by recurrent attacks. Cautions. Doctors deliver the treatment via injection. Max Units (per dose and over time) [HCPCS Unit]: Indication Billable Units Per # days Cervical Dystonia 200 84 Chronic Migraine Prophylaxis 100 84 Common treatments for migraines, such as Botulinum toxin type A (e. BOTOX® prevents migraine attacks before they even start, and can reduce up to 9 migraine days a month. Dysport 300 unit Injection: 1 vial per 84 day supply Dysport 500 unit Injection: 3 vials per 84 day supply Dysport 500 unit Injection: 1 vial once (for Ventral Hernia only) B. Keep this leaflet with the medicine. 13 Subsequently, off-label coverage has been extended for Botox® and Dysport as a treatment of hemifacial spasm in adults. This is crucial for migraine patients as it directly targets the pain pathways, potentially reducing the frequency and severity of migraine attacks. Inject into target muscle(s) within 24 hours of reconstitution. P. You may need to read it again. When injecting, hold the syringe at Botulinum Toxin is well accepted as a treatment for migraines. Is this guidance up to date? We reviewed the evidence in January 2016. INDICATION. How long does it take for Dysport to work? Botox for Chronic Migraine . 3 BoNT injection is probably ineffective for treating chronic tension-type headaches (two Class I Do not receive a Dysport injection if: you are allergic to Dysport or any of its ingredients, or cow’s milk protein; you had an allergic reaction to any other botulinum toxin product, such as Myobloc®, Botox®, or Xeomin®; or you have a skin infection at the planned injection site. DYSPORT is indicated for the treatment of adults with cervical dystonia. Jun 24, 2024 · C-BEOND will examine Dysport for chronic migraine (at least 15 days of headaches, 8 of which were migraines, per month), while E-BEOND focuses on episodic migraine (fewer than 15 headache days per month with at least six days being migraine days). Mar 31, 2022 · Individuals suffering from migraines may have a variety of problems, such as sickness absence and reduced productivity at work, school, and home. Dysport injections into the jaw muscles can help relieve tension and reduce pain associated with TMJ. Dec 22, 2015 · Botox is currently the only neuromodulator FDA approved to treat migraines, but that being said, Dysport and Xeomin can also both be used off-label to help with chronic migraines. Sep 3, 2018 · London Aesthetic Migraine Protocol. Dysport 300 unit Injection: 1 vial per 84 day supply Dysport 500 unit Injection: 3 vials per 84 day supply B. I recommend visiting a board-certified dermatologist with experience using neuromodulators to treat chronic migraines for an in-person evaluation and discussion of Feb 26, 2021 · AbobotulinumtoxinA (ABO, Dysport ®, Ipsen, Billancourt, France) was not included in this evaluation as its potency labelling is substantially different from the potency labelling of ONA and INCO. Published April 2022 . adults (18% to 26% of women and 6% to 9% of men) have experienced a migraine, according May 5, 2016 · This article summarizes information provided in the complete guideline, available on the Neurology® Web site at Neurology. FDA-Approved Facial Sites for Botox and Dysport Size Effects Jun 25, 2023 · Dysport is meant for use on the vertical lines that form between the eyebrows (glabellar lines). Data sources CENTRAL, MEDLINE, Embase and trial registries. Sep 14, 2023 · The purpose of this study is to understand the safety and effectiveness of the study drug, Dysport® when compared with placebo in preventing episodic migraine. . Believed by the patient to be migraine at onset and relieved by a triptan or ergot derivative May 7, 2024 · Migraines affect millions of people worldwide, causing debilitating pain, sensitivity to light, and nausea. 877. According to the World Health Organization, migraines are the third most common disease globally, with an estimated 1 in 7 adults experiencing these intense headaches. Botox is meant for use on glabellar lines, forehead lines, and crow’s feet (laugh lines) around reach the bottom of the Dysport vial when drawing up the reconstituted toxin. May 12, 2023 · Some 14% of global prevalence, based on high-income country populations, suffers from migraine. Dysport should be used for only one injection session and for only one patient after reconstitution. The study drug being tested is Dysport®, a botulinum toxin type A (BoNT-A) naturally produced by a certain type of bacteria, which has already been approved as a medicine in over 90 countries (including US) for different medical conditions, but not in prevention of migraines yet. Available as a series of injections, Botox treatment seeks to prevent headaches for those with chronic migraine, with most people affected seeing improvement after treatment. Dec 24, 2023 · Serious side effects of Dysport. A Comparison of Acute Treatment Regimens for Migraine in the Emergency Department ; Effectiveness of standardized combination therapy for migraine treatment in the pediatric emergency department. 1,3 Over 5M BOTOX ® treatments have been delivered to more than 850,000 patients since FDA approval in 2010. Because safety hasn’t been established, you shouldn’t get this treatment if you’re pregnant or breastfeeding. However the PREEMPT Protocol is now 5 years old and can be Jun 27, 2012 · Evidence-based recommendations on botulinum toxin type A (Botox) for preventing headaches in adults with chronic migraine. Participants will need to complete an e-diary and questionnaires throughout the study. Has the same active neurotoxin (botulinum toxin type A) but differs from onabotluinumtoxinA by its method of purification. Botox and Dysport have additional support in the IBM Micromedex compendium DrugDex for off-label treatment of hemifacial spasm in adults. On the day of your procedure, here’s what you should keep in mind. To ease migraine symptoms, Botox is injected into the treatment area. What is Dysport Dysport is a muscle relaxant produced by Clostridium botulinum bacteria. 1 day ago · INDICATION. ⁵˒⁶ The first of the studies found onabotulinumtoxinA was ineffective at changing total headache episodes but did provide a noticeable change in the frequency of headache days/28 days Episodic Migraine Strong Evidence OnaBoNT-A should not be offered as a treatment for episodic migraine (Level A). Tables e-1 through e-6 and appendices e-1 through e-5, cited in the full guideline (data supplement), as well as references e1 through e16, cited in this summary, are available at Neurology. Dysport is not interchangeable with other botulinum toxins, and the potency units are not the same. I’ve always heard that Botox and DY sport help with migraines. 2 Glabellar Lines DYSPORT is indicated for the temporary improvement in the appearance of moderate to severe glabellar lines associated with procerus and corrugator muscle activity in adult patients less than 65 years of age. Muscles Injected Recommended Dose DYSPORT (U) Wrist Flexors Flexor carpi radialis (FCR) 100-200 U Flexor carpi ulnaris (FCU) 100-200 U Finger Flexors Studies show Botox and Dysport, after dosage modification, may be equal in effectiveness. Max Units (per dose and over time) [HCPCS Unit]: Indication Billable Units Per # days Cervical Dystonia 200 84 Chronic Migraine Prophylaxis 60 84 Sialorrhea 100 84 abobotulinumtoxinA (aboBoNT-A) = Dysport® (Medicis Pharmaceutical Corp. BLA 103000/5308, PMR 2469-1 BOTOX (onabotulinumtoxinA) injection 5 Table of Figures Figure 1: 191622-103 Design Phase 3 Chronic Pediatric Migraine Study Oct 5, 2023 · Key Points. A referral is not required for chronic migraines, call us to book a complimentary consultation. D. Slight headache that lasts for several hours after treatment. If you have any concerns about taking this medicine, ask your doctor or pharmacist. , avoiding migraine triggers, pharmacotherapy, behavioral therapy, physical therapy, etc. Food and Drug Administration (FDA)-approved for the treatment of chronic migraines. It acts on the Sep 26, 2018 · OnabotulinumtoxinA should be administered according to the PREEMPT injection protocol, i. +1. CM is characterized by headache on >15 days per month, of which at least 8 headache days per month meet criteria for migraine without aura or respond to migraine-specific treatment. Apr 26, 2016 · Since 2008, new studies addressing the possible benefits of commercially available BoNT pharmacology have come to light, including 2 PREEMPT trials that investigated the use of BoNT for chronic migraine. A total of 128 patients with migraine without aura were enrolled. SMD form protocol master data–5- INT / Version 1 In the second Treatment Phase, all participants will get Dysport® (Dose A or Dose B). A migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head, and is often accompanied by feeling or being sick and a sensitivity to American Academy of Ophthalmic Executives® Fact Sheet: Coding Botox A for Treatment of Migraine . A 12-week, double-blind, randomized trial of Dysport (120 or 240 units) vs placebo was conducted in 6 centers in Thailand to evaluate the efficacy, safety, and optimum dose of botulinum toxin type-A (Dysport) for migraine prophylaxis. 5 million U. Dec 22, 2023 · Unique Protocol ID: A-38-52120-007 : Brief Title: Dysport® In Migraine Without Aura Prophylaxis : DIMWAP Study : Official Title: A 12-Week Prospective, Double-Blinded, Randomized, Multicenter Study of Low Dose and Medium Dose Botulinum Toxin Type A (Dysport® ) Injection for Migraine Prophylaxis. Dysport® can be used to treat a number of neuromuscular conditions, including chronic migraine. injecting 155 U–195 U to 31–39 sites every 12-weeks. Food and Drug Administration (FDA) for various other conditions including bladder dysfunction, chronic migraine, upper limb spasticity, cervical dystonia, primary axillary Sep 30, 2023 · 2. 1 Instructions for Safe Use. Patients with chronic migraine are less successful in their career and have lower income . Estimated doses for the treatment of frontal headaches is from 75 to 150 units of Dysport. Guidance development process. You can find out more and book an appointment here. Jul 9, 2020 · Botox aftercare also includes some precautions. Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac. After reconstitution, DYSPORT should be used for only one injection session and for only one patient Cervical Dystonia (2. 2004, Broomfield, Colorado Nov 16, 2010 · A 12-week, double-blind, randomized trial of Dysport (120 or 240 units) vs placebo was conducted in 6 centers in Thailand to evaluate the efficacy, safety, and optimum dose of botulinum toxin type-A (Dysport) for migraine prophylaxis. Design Systematic review and meta-analysis. The FDA approved Botox/ Dysport for migraines recently (just a few months before I started in January, I believe). H. Furthermore, many patients with chronic migraine also live with central nervous system sensitivity and can experience a “Botox Flare” immediately after their procedure. 1 Units of biological activity of Dysport cannot be compared to or converted into units of any other botulinum toxin products 1500U of DYSPORT were not investigated for the treatment of upper limb spasticity in adults. Dysport is a muscle relaxant produced by Clostridium botulinum bacteria. It acts on the Botox now has proven to be an effective treatment for reducing chronic headaches. The National Migraine Centre provides access to expert clinicians who can provide Botox treatment for migraine in the UK. We recommend that patients are defined as non-responders, if they have less than 30% reduction in headache days per month during treatment with onabotulinumtoxinA. There will be 3 in person visits and 4 remote visits. Clear dosing guidance for adult cervical dystonia . ). They’re “neurotoxins,” medications that Botox for Chronic Migraine Overview. − Dysport 500 unit single-dose vial for injection: 3 vials per 84 day supply − Dysport 500 unit single-dose vial for injection: 1 vial once (for Ventral Hernia only) B. 2. 3) • Initial dose is 500 Units given intramuscularly as a divided dose among the affected muscles Sep 15, 2022 · Botox is an effective migraine treatment that has helped many people with chronic migraines. for migraine without aura and/or criteria B and C for migraine with aura (C) On ≥8 days/month for >3 months, fulfilling any of the following: 1. It is injected into several muscle groups in the face and head, relaxing those muscles. e. Hypersensitivity. • Chronic migraine headache AND • The patient has a persistent history of chronic, debilitating migraine headaches with frequent attacks on 15 or more days per month for longer than 3 months AND • A neurologist has thoroughly evaluated the patient and has established a diagnosis of chronic migraine headaches; AND The purpose of this study is to understand the safety and effectiveness of the study drug, Dysport® when compared with placebo in preventing chronic migraine. It is likely that treatment with Dysport for frontalis and glabellar rhytids will uncover migraine patients who find relief from this modality. 6585 SAN FRANCISCO EMDR Protocol for Headache The Protocol Phase 1 : History Taking-Treatment Planning Phase 2 : Preparation Phase 3 : Assessment Phase 4-7 : Desensitization-Closure The purpose of this study is to evaluate the efficacy of botulinum toxin type A (Dysport®) injections into pericranial muscles compared to placebo to prevent migraine attacks. ; This is given as 0. yf kg xr yu es mc ae sy yn na